Utility library for structural bioinformatics

Utility library for structural bioinformatics

In this Note we present a new software library for structural bioinformatics. The library contains programs, computing sequence- and profile-based alignments and a variety of structural calculations with user-friendly handling of various data formats. The software organization is very flexible. Algorithms are written in Java language and may be used by Java programs. Moreover the modules can be...

Structural bioinformatics

Motivation: Protein-protein complexes are known to play key roles in many cellular processes. However, they are often not accessible to experimental study because of their low stability and difficulty to produce the proteins and assemble them in native conformation. Thus, docking algorithms have been developed to provide an in silico approach of the problem. A protein-protein docking procedure ...

Structural Bioinformatics for Protein Engineering

Structural bioinformatics The Victor C11 library for protein representation and advanced manipulation

Motivation: Protein sequence and structure representation and manipulation require dedicated software libraries to support methods of increasing complexity. Here, we describe the VIrtual Constrution TOol for pRoteins (Victor) Cþþ library, an open source platform dedicated to enabling inexperienced users to develop advanced tools and gathering contributions from the community. The provided appli...

Bioinformatics III: Structural Bioinformatics and Genome Analysis